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Eugenics. Not the racist BS that was done in the past, but really pushing the limit to see if we can breed super humans. Genetic editing to make humans immune to cancer or disease. Increased lifespan. Resistance to radiation. Smarter. Stronger. Better.
Arguably, this kind of thing is actually somewhat of a necessity if we ever want to explore the stars. We are far too fragile in our current bodies to survive the difficulties and vastness of space.
Honestly, I'd be super stoked if we could just get rid of all the actual serious defects, just, whack a few moles that really super suck for anyone who gets the short end of the genealogical stick.
And by that I mean like