That depends. Are you doing this just for your own enjoyment or trying to use that art for commercial purposes? Do you have the artist's permission to modify and pass on their work?
If it's just for you then go hog wild. If you're planning to use the modified art commercially or post it online publicly you should get the artist's permission first.
They are. The Republican playbook in every state is to slash education funding, make abortion and birth control as hard to access as possible and then wait 20-30y for a big poorly educated population to grow that they can control easily with media and the Jesus