Fair enough, I used to be scientist (a very bad one that never amounted to anything) and my perspective has been that the major barriers to progress are:
- We've just got all the low hangingfruit
- Science education isn't available to many people, perspectives are quite limited consequently.
- power structures are exploitative and ossified, driving away many people
- industry has too much influence, there isn't much appetite to fund blue sky projects without obvious short term money earning applications
- patents slow progress
- publish or perish incentivises excessive volumes of publication, fraud, and splitting discoveries into multiple papers which increases burden on researchers to stay current
- nobody wants to pay scientists, bright people end up elsewhere
They uh, still do the same thing fundamentally
Altman isn't gonna let you blow him dude