Depends, if it's only biological changes, I'd get myself two hearts, and minimize the chances of any disease or aging knocking me out, then become an anthro folf because being hooman is overrated
If cybernetics are allowed, I'd probably get rid of the damn body and just have a virtual one, with my brain connected to some machine deep underground
I think hands with pawpads and some proper claws are a good compromise :3
I'd be an anthro, so all the benefits of being hooman without being hooman (except sweating, so you'd be able to outrun me eventually)