Chetzemoka

Yeah, long QT syndrome is estimated around 1/2000 people. Relatively rare. I fully confess that I'm just traumatized by my personal experiences with patients taking the drug lol

Hahaha, I love working with older folks. They're my favorite patients.

I actually WOULD recommend this for seniors. It does not have any anticholinergic side effects like a lot of pharmaceutical sedatives do, and it doesn't interact with the most common blood pressure or cardiac meds that older folks often take.

I have the same problem with magnesium supplements. Mag glycinate has less of that laxative effect than mag citrate, so she could try that as well.

The only two caveats I would add are: she should definitely tell her doctors she's taking it, as with any OTC supplement. And if she's specifically on a drug called warfarin (Coumadin), she should be very cautious. (Even Tylenol can cause warfarin to build up in the body. Warfarin sucks, so we don't use it as much anymore, but it's not unheard of.)

Hope that helps! (I'm a cardiac nurse. I work with older folks a lot.)

Yep, that's the usual recommended dose - 200mg like an hour before bedtime

Yeah, medically cyclic vomiting syndrome is usually more associated with cannabis abuse disorder, so you're probably not going to get far trying to get that diagnosis specifically. But that doesn't mean these same treatment regimens won't help. Think of it as physical therapy for the gut and nervous system.

Oh man, you are really challenging my senior citizen brain here. I think I know how to bold things haha

I like Nootropics Depot as a source company. They sell it for $20 for a 30 count bottle of 200mg capsules.

It's really safe even in absolutely large doses. (There are studies performed using doses in the multiple GRAM range.) I highly recommend trying it. Personally I take 400mg/night, which is twice the dosage you'll see advertised. I only mention because I think the standard advertised range is probably too low for people like me.

Coenzyme Q10

Energy, mitochondrial support, antioxidant

Personally, I think everyone should be taking this. Extremely safe, improves cardiac outcomes, some evidence that it can reverse damage in chronic kidney disease. Most people won't feel different, but I take high dose CoQ10 for mitochondrial dysfunction, and I can tell you it definitely has a huge impact. Love this stuff.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8092430/

https://www.mdpi.com/2076-3921/8/2/44#:~:text=Chronic%20Kidney%20Disease%20(CKD),-The%20role%20of&text=There%20is%20evidence%20that%20CoQ10,dialysis%20in%20patients%20with%20CKD.

Apigenin (herbal supplement)

Insomnia, anxiety

Derived from chamomile flowers (and other plant sources), I've found this to be more successful in treating my chronic insomnia than any of the pharmaceutical options. (And believe me, I've tried them all.)

I am so sorry that she's dealing with this. I've heard of successful treatment of intractable nausea using biofeedback therapy. The idea being that the body gets stuck in a negative feedback loop and trying to reverse that back to previous functioning.

https://www.researchgate.net/publication/314851129_Biofeedback_and_visualization_to_control_nausea_and_vomiting

https://pubmed.ncbi.nlm.nih.gov/21154016/#:~:text=Treatment%20outcome%20suggests%20that%20vomiting,bodily%20control%20and%20self%2Defficacy.

I hope this gets better for her.

Heads up to anyone with cardiac issues, especially long QT syndrome or other meds that prolong the QT internal: Ondansetron is so notorious for QT prolongation and cardiac arrhythmia problems that we have to perform an EKG before we're allowed to give you a second dose on our cardiac unit.

I have scary anecdotes that bias me against it lol

Low Dose Naltrexone is amazing for all kinds of chronic pain and inflammation.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3962576/