Chetzemoka
Contagion (2011) remains the scariest movie I've ever seen, even now that I've lived it. Just imagining an encephalitic virus with a 20-30% mortality rate like the one depicted in the movie makes me nauseous. (Loosely based on real life Nipah virus.)
Birds and wildlife in my neighborhood. I'm technically in suburbia, but enough old growth patches have been maintained that we have a surprising amount of wild animals that live in or travel through the neighborhood (Massachusetts, US)
Merlin app is amazing for identifying birds at the feeder I put on my back deck. And the rest of the animals, I mentally collect like Pokemon.
Same. Airplanes. Seeing them, being on one, just so giddy and excited every time.
Tenet. I know it became fashionable to hate it, but it's my favorite Christopher Nolan movie because it's just fun to watch, which is not common with Nolan movies.
I think John David Washington and Robert Pattinson have great chemistry. You need to be comfortable with being clueless about what's happening because the story is told from the limited perspective of the main character. If he doesn't know, the audience doesn't know. When he finds out, you find out. So what the movie seems to be "about" shifts a few times based on his perspective and his assumptions.
Yes, it's clearly just an excuse for Christopher Nolan to indulge in impossible looking practical effects scenes and I love it.
The most effective medication is the one that actually gets used.
Huh, now that's super interesting.
Ok you and I both have to go to sleep, but now you've got me wondering about the eternal debate amongst our medical residents about benzos vs. barbiturates for acute alcohol withdrawal. I'll have to read up on this some more
Oh you're getting in the weeds now hahaha. Looks like it's primarily GABA_A
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5326685/
I just had to look that shit up haha. I've never thought to check into it beyond just "you're not breathing, so I'm about to make you very angry by reversing your high, sorry bro" lol
So, it's interesting, because it's well-known to have effects on the same GABA receptors as benzodiazepines (like Xanax), but none of the addictive, physical dependence problems, and apigenin doesn't respond consistently to the drug we use to reverse benzos (called flumazenil).
So... we're not entirely sure? It could still be the GABA effects that help with sleep. But there's also a host of antiinflammatory neurological effects that probably better explain its efficacy against Alzheimer's, for example.
Now, if you really want to put yourself to sleep, feel free to crawl through this alphabet soup of a research article lol:
Here, I found a good article for you:
https://www.uspharmacist.com/article/assisting-seniors-with-insomnia-a-comprehensive-approach
Literally the only thing that gives me refreshing sleep. (See also: mitochondrial dysfunction that I mentioned in my other comment about CQ10.) Apigenin seems to improve what's called "sleep architecture" in a way that none of the pharmaceuticals I've ever tried do.
War of the Worlds (2005) with Tom Cruise is easily one of the most stressful movies I've ever seen, and I love it.