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During my statistics graduate degree, there was one course we had to do our data analysis using SAS. I absolutely despise it and refuse to work for any employer that would expect me to use it.
SPSS is also crap - at my current job there were some processes that used it's scripting "language". It was both painful but cathartic to slowly rewrite those processes into R.
Sas is awful but I will say doing mixed linear models and doing contrasts was pretty easy compared to r.