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Denuvo respond to their rep for tanking games - "I'm a gamer myself, and therefore I know what I'm talking about"
(www.rockpapershotgun.com)
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Going by that logic, there's simply no way that Denuvo does not hinder performance.
That's also a lie. There is no way it would be impossible to remove the protection code (or parts of it) or make it not execute. That alone makes him a clown.
Not to mention that some of the cracks are incredibly lightweight in the first place so even disabling a small amount of their code would improve things. Removing the encryption mechanisms alone works wonders.