this post was submitted on 16 Sep 2023
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Researchers from Pritzker Molecular Engineering, under the guidance of Prof. Jeffrey Hubbell, demonstrated that their compound can eliminate the autoimmune response linked to multiple sclerosis. Researchers at the University of Chicago's Pritzker School of Molecular Engineering (PME) have developed

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[–] [email protected] 371 points 1 year ago (32 children)

This article is garbage but I'm a molecular biologist and the publication they're talking about is really neat.

The "ELI5 to the point of maybe reducing out the truth" way to explain it is that the researchers can add "flags" to proteins associated with immune responses that make cells pick them up and examine them. This is shown to work for allergins (so say, add a flag to peanut protein and the cells can look at it more closely, go "oh nvm this is fine" and stop freaking out about peanuts) as well as autoimmune diseases (where cells mistake other cells from the same body as potential threats).

It's not nearly to a treatment stage, but tbh this is one of the more exciting approaches I've seen, and I do similar research and thus read a lot of papers like this.

There's a lot of evidence that we are entering a biological "golden age" and we will discover a ton of amazing things very soon. It's worrysome that we still have to deal with instability in other parts of life (climate change, wealth inequality, political polarization) that might slow down the process of turning these discoveries into actual treatments we can use to make lives better...

Still, don't doubt everything you read! A lot of cool stuff is coming, the trick is getting it past the red tape

[–] [email protected] 10 points 1 year ago (7 children)

The privacy on that site was horrible, and I stoped de-selecting vendors who want permission to track me after two minutes.

But I wanted to ask you: are there any biologics based on this discovery in phase I or even II at this point? Any odds on one of them making it to III?

(also re: your last comment, read William Gibson's The Peripheral; you are describing his "jackpot" scenario)

[–] [email protected] 2 points 1 year ago (1 children)

privacy on that site was horrible, and I stoped de-selecting vendors who want permission to track me after two minutes.

Just open the page in a private window at that point, and click the "yeah sure track everything bro" button.

[–] [email protected] 4 points 1 year ago (2 children)

"Private browsing" is for not letting your mom see your porno history on the family computer, it does fuck all for you being tracked online.

[–] [email protected] 3 points 1 year ago (1 children)

It deletes the cookies from Incognito, if you only open that site in incognito and then close the tab, it does nothing.

[–] [email protected] 2 points 1 year ago (1 children)

It still knows your IP and browser fingerprinting still works, they still know who you are and what sites you visit. If you change your VPN server you're a little closer, and of course there's Tor assuming you don't get a malicious exit/entry node set, but private browsing isn't as private as people seem to expect.

[–] [email protected] 1 points 1 year ago
[–] [email protected] 1 points 1 year ago

It’s actually good in firefox and safari, just don’t use chrome

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