this post was submitted on 11 Jun 2025
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Text to avoid paywall

The Food and Drug Administration is planning to use artificial intelligence to “radically increase efficiency” in deciding whether to approve new drugs and devices, one of several top priorities laid out in an article published Tuesday in JAMA.

Another initiative involves a review of chemicals and other “concerning ingredients” that appear in U.S. food but not in the food of other developed nations. And officials want to speed up the final stages of making a drug or medical device approval decision to mere weeks, citing the success of Operation Warp Speed during the Covid pandemic when workers raced to curb a spiraling death count.

“The F.D.A. will be focused on delivering faster cures and meaningful treatments for patients, especially those with neglected and rare diseases, healthier food for children and common-sense approaches to rebuild the public trust,” Dr. Marty Makary, the agency commissioner, and Dr. Vinay Prasad, who leads the division that oversees vaccines and gene therapy, wrote in the JAMA article.

The agency plays a central role in pursuing the agenda of the U.S. health secretary, Robert F. Kennedy Jr., and it has already begun to press food makers to eliminate artificial food dyes. The new road map also underscores the Trump administration’s efforts to smooth the way for major industries with an array of efforts aimed at getting products to pharmacies and store shelves quickly.

Some aspects of the proposals outlined in JAMA were met with skepticism, particularly the idea that artificial intelligence is up to the task of shearing months or years from the painstaking work of examining applications that companies submit when seeking approval for a drug or high-risk medical device.

“I don’t want to be dismissive of speeding reviews at the F.D.A.,” said Stephen Holland, a lawyer who formerly advised the House Committee on Energy and Commerce on health care. “I think that there is great potential here, but I’m not seeing the beef yet.”

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[–] [email protected] 16 points 3 days ago

Great, now I have to start proof-reading any communications I get from the FDA to make sure it didn't hallucinate a scientific article in the citations. There's going to be so many Vegetative Microscopy proposals.

[–] [email protected] 12 points 3 days ago (1 children)
[–] [email protected] 3 points 2 days ago

Wherever we're going, we're making great time!

[–] [email protected] 3 points 2 days ago

My experiences with most AI is that you really, really need to double check EVERYTHING they do.

[–] [email protected] 10 points 3 days ago* (last edited 2 days ago) (4 children)

Discouraging use of ~~artificial~~ dye is a good idea. It interferes with people's ability to make health conscious choices. Requiring labeling would be a great start.

Food dye is used to cover up a lot of food crime. Most of us wouldn't eat food that needs to be dyed to look safe to eat, if it weren't dyed, if we had a choice.

Using AI to fast track food regulations is a terrible idea.

Edit: Good point that "artificial" is part of their witch hunt wording. I only mean we could probably do with less dye use, or clear labels on what has been dyed.

[–] [email protected] 5 points 2 days ago

its coming from worm brains who consumes methlyene blue, which is a dye in itself.

[–] [email protected] 8 points 3 days ago* (last edited 3 days ago) (3 children)

I also prefer 100% natural ground insects in my food over artificial dyes.

(Just teasing for funsies)

[–] [email protected] 2 points 2 days ago

Ricin is natural and one of the most potent plant-produced poisons.

[–] [email protected] 5 points 3 days ago

yeah, some people craze over all natural and I tell them some natural ingredients just to see them pause, like beaver bits make vanilla taste better so is a natural addictive. idc, it taste good, but some people question thier vanilla.

[–] [email protected] 4 points 2 days ago* (last edited 2 days ago)

Haha. Fine by me, if it's clearly labeled.

Edit: I'm not eating any bugs, if I know they're present...unless they're truly delicious...

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[–] [email protected] 8 points 3 days ago

is this the onion?

[–] [email protected] 8 points 3 days ago

You really should put testing and verification in the hands of a new and unproven technology just to save a few bucks. Don't worry, the ramifications are trivial, just drug safety.

[–] [email protected] 7 points 3 days ago

Cocaine for everyone!

[–] [email protected] 7 points 3 days ago

Niether solution is good but I feel id rather have confidence a drug is safe, even if I had to wait, rather then un-sure but quickly. I understand terminally ill wants quick, but isn't there already a system to get unproven medication, just you accept risk?

[–] [email protected] 3 points 2 days ago

The guy on the photo has the bottom half of a huge head and the eyes up of a small head. Totally weird.

[–] [email protected] 3 points 3 days ago

Eventually a utopia society will just be filled with A.I. talking to other A.I. and training more A.I. to do A.I. things. No need for humans, those dont have any value.

[–] [email protected] 2 points 3 days ago

The same AI that time after time, even when I tell it the version of the app and OS that I'm using, continues to give me commands that are incompatible with my version? If I tell it the command doesn't work it eventually loops back to its original suggestion.

[–] [email protected] 1 points 3 days ago

Quick! Someone send tell the AI that this is what you need to sequence to make medicine! 😏

[–] [email protected] 0 points 2 days ago* (last edited 2 days ago) (1 children)

This could be a good use of AI. Since this regime is doing it, and since some of their claims are pretty unrealistic, it probably won't be. But, ML has been used for a while to help identify new drug compounds, find interactions, etc. It could be very useful in the FDA's work - I'm honestly surprised to hear that they're only just now considering using it.

The Four Thieves Vinegar Collective uses some software from MIT ASKCOS that uses neural networks to help identify reactions and retrosynthesis chains to produce chemical compounds using cheap, homemade bioreactors. Famously, they are doing this to make mifepristone available for people in areas of the US without access to abortion care.

You can check it out here. It's a good example of a very positive use-case for an AI/ML tool in medicine.

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[–] [email protected] -4 points 3 days ago

Putting periods in acronyms is some 90s shit.

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